Single Camera Colonoscopy (SCC)

Modern colonoscopes are high-quality instruments with outstanding optics and excellent handling characteristics.

However, they contain a single video camera with an angle of view ranging from 140° to 170°, and this limits their ability to see behind folds and flexures.

Clinical research has shown that:

  • Standard colonoscopy misses at least 24% of adenomas 1-3 and 12% of large adenomas (≥1 cm).4-6
  • Large adenomas progress to cancer at a rate of 2-5% per year.7
  • 7% of colorectal cancers in the U.S. are “interval cancers,” occurring within a few years after a colonoscopy.8
  • Over half of interval cancers in the U.S. (about 6,000/year) result from missed lesions – mostly large adenomas.8,9
  • 2/3 of missed adenomas are hidden behind folds.4

The Third Eye Panoramic Device Offers a Solution

  • Two side-viewing cameras supplement the colonoscope’s forward view to create a panoramic video image (approximately 330°) that reveals areas behind folds and flexures.
  • The device works with all standard adult or pediatric colonoscopes from the three major manufacturers, so endoscopists can continue using the scopes that they prefer.
  • It maintains a free working channel to allow passage of instruments for polypectomy and to maximize suctioning of fluid and debris.
  • The Third Eye Panoramic device was cleared by the FDA for marketing in the U.S. in November 2014.

How It Works

The Third Eye Panoramic device is placed on the distal tip of the colonoscope prior to beginning the procedure. The examination technique is identical to standard colonoscopy except that the endoscopist has a panoramic view of the colon throughout insertion and withdrawal.

The proximal end of the Third Eye Panoramic device plugs into a video processing unit that enables the left, middle and right images to be viewed on a single flat panel video monitor.

The Third Eye Panoramic device can be used with standard colonoscopes manufactured by Olympus, Pentax and Fujinon in both adult and pediatric sizes.

See Instructions for Use packaged with product for detailed operating instructions.

Low Cost, Multi-Use Device Enhances Quality

The latest version of the Third Eye Panoramic is resposable, meaning that it can be used multiple times prior to disposal.  Thus, the resposable device provides an ultra-wide-angle view of the colon at low cost per procedure.  The cleaning and disinfection protocols for the Third Eye Panoramic are similar to the methods used to reprocess colonoscopes between uses. 

Procedural Video

0:00 – Scope is in the cecum, with ileocecal valve in left-side view.
0:05 – NBI is activated on colonoscope, with no interference from laterally-directed LEDs.
0:10 – Withdrawing through distal ascending colon
0:16 – A polyp appears in the right-side view. Although not initially seen in the colonoscope’s view, once the endoscopist is aware of its existence, he is able to deflect the colonoscope’s tip up and to the right to bring the polyp into view at 0:36.
0:40 – Withdrawing through the sigmoid, the colonoscope naturally tracks around the outer curve of a flexure, leaving a “blind spot” in the inner curve distal to the flexure. The endoscopist uses the left lateral camera to view the area behind the flexure and folds.
0:56 – In another flexure, the left lateral camera again shows the inner curve and the area behind it.


Dr. Moshe Rubin and his team of investigators at New York Hospital Queens Weill Cornell Medical College presented the results of a feasibility study of the Third Eye Panoramic device at Digestive Disease Week (DDW) in Washington, D.C. on May 17, 2015.


Poster Presentation from DDW 2015
Use of Third Eye Panoramic Device Expands the View of a Standard Colonoscope.


  1. Rex DK, Cutler CS, Mark DG, et al. Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies. Gastroenterology 1997;112:24-8.
  2. Van Rijn JC, Reitsma JB, Stoker J, et al. Polyp miss rate determined by tandem colonoscopy: A systematic review. Am J Gastroenterol 2006;101:343-50.
  3. Heresbach D, Barrioz T, Lapalus MG, et al. Miss rate for colorectal neoplastic polyps: A prospective multicenter study of back-to-back video colonoscopies. Endoscopy 2008;40:284-90.
  4. Pickhardt PJ, Nugent PA, Mysliwiec PA, et al. Location of adenomas missed by optical colonoscopy. Ann Intern Med 2004;141:352-9.
  5. Hewett DG, Rex DK. Miss rate of right-sided colon examination during colonoscopy defined by retroflexion: an observational study. Gastrointest Endosc 2011;74:246-52.
  6. Siersema, PD, Rastogi A, DeMarco DC, et al. Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup. World J Gastroenterol 2012;18:3400-8.
  7. Brenner H, Hoffmeister M, Stegmaier C, et al. Risk of progression of advanced adenomas to colorectal cancer by age and sex: estimates based on 840,149 screening colonoscopies. Gut 2007;56:1585-9.
  8. Cooper GS, Xu F, Barnholtz-Sloan JS, et al. Prevalence and Predictors of Interval Colorectal Cancers in Medicare Beneficiaries. Cancer 2012;118:3044-52.
  9. Robertson DJ, Lieberman DA, Winawer SJ, et al. Interval Cancer After Total Colonoscopy: Results from a Pooled Analysis of Eight Studies. Gastroenterology 2008;134:A111-2.

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